Aromasin Rebound Effect?  

Page 1 / 2
  RSS

maxzax
(@maxzax)
Active Member
Joined: 10 months ago
Posts: 5
28/10/2018 6:38 am  

Hey Guys,

I like to know if you could help me out.

I was looking at getting some aromasin to lower my estrogen levels. My total E's are high (219 range 40-115) and E2 levels are at the top of the reference range. Which I believe is causing HPTA suppression.

From the information I've read Arimidex doesn't make much of a difference in total E's and I've read from other's experiences that aromasin will lower total E's, so I am looking at using aromasin.

I've read that aromasin is a suicide Estrogen Inhibitor, if I lower my Estrogen levels too much with aromasin, will they rebound back to appropriate levels?

Thanks guys!


Quote
Big Cat
(@big-cat)
Member Moderator
Joined: 1 year ago
Posts: 313
28/10/2018 7:13 am  

Probably higher initially since the absence of estradiol increases presence of both aromatase and the estrogen receptor. THe first weeks following you are likely to have more estrogen and more sensitivity to estrogen.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


ReplyQuote
Neuromancer
(@neuromancer)
Active Member
Joined: 12 months ago
Posts: 8
28/10/2018 8:10 am  

BC, to your knowledge is it true that steroidal AI's cause less of a rebound?


ReplyQuote
Big Cat
(@big-cat)
Member Moderator
Joined: 1 year ago
Posts: 313
28/10/2018 9:07 am  

only because they are less potent.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


ReplyQuote
maxzax
(@maxzax)
Active Member
Joined: 10 months ago
Posts: 5
28/10/2018 10:02 am  

BC,

If you know of any studies or test results on Aromasin, can you please post them for me.

So based on your information, there would be a large rebound during the first week and after that the levels would stay low?

Btw, thanks for all your knowledge learned a lot from your many posts.

Thanks!

Posted by: Big Cat
Probably higher initially since the absence of estradiol increases presence of both aromatase and the estrogen receptor. THe first weeks following you are likely to have more estrogen and more sensitivity to estrogen.

ReplyQuote
Big Cat
(@big-cat)
Member Moderator
Joined: 1 year ago
Posts: 313
28/10/2018 10:46 am  

You'd have a large rebound the first few weeks, and then levels of estradiol will normalize again.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


ReplyQuote
oswaldosalcedo
(@oswaldosalcedo)
Estimable Member
Joined: 12 months ago
Posts: 173
28/10/2018 11:39 am  

QUOTE]Originally posted by Big Cat
Probably higher initially since the absence of estradiol increases presence of both aromatase and the estrogen receptor. THe first weeks following you are likely to have more estrogen and more sensitivity to estrogen. [/QUOTE]

not necessarily, i have very low levels of estradiol (under low limits) and i use 2 gr of test (weekly), but my estradiol levels are the same (low always).

to say absence, is extreme,because there is something always.

dr frankenstein


ReplyQuote
maxzax
(@maxzax)
Active Member
Joined: 10 months ago
Posts: 5
28/10/2018 12:24 pm  

Hi oswaldosalcedo,

Was you your low Estradiol caused by using aromasin (exemestane)? If not, what caused the low estradiol levels for you?

What are the side effects your experiencing from having low estradiol levels?

Your answers to the above questions would be much appreciated.

Thank you!!!
Max


ReplyQuote
oswaldosalcedo
(@oswaldosalcedo)
Estimable Member
Joined: 12 months ago
Posts: 173
28/10/2018 1:01 pm  

really i dont know.
genetic predisposition (maybe).

dr frankenstein


ReplyQuote
maxzax
(@maxzax)
Active Member
Joined: 10 months ago
Posts: 5
28/10/2018 1:32 pm  

Thanks for the response oswaldosalcedo,

Do you suffer from any negative symptoms of having low estrogen levels?

Thanks!!
Max

Posted by: oswaldosalcedo
really i dont know.
genetic predisposition (maybe).

ReplyQuote
triguy
(@triguy)
Eminent Member
Joined: 1 year ago
Posts: 40
28/10/2018 2:20 pm  

would tapering armidex avoid the rebound?

what would the taper look like?


ReplyQuote
maxzax
(@maxzax)
Active Member
Joined: 10 months ago
Posts: 5
28/10/2018 3:05 pm  

I believe you want the rebound, because adex and Aromasin are anti E's made for females and could be too strong for men.

Males need estrogen as well for libido, erections and sexual functioning. Too much isn't good and too little isn't good from my understanding.


ReplyQuote
oswaldosalcedo
(@oswaldosalcedo)
Estimable Member
Joined: 12 months ago
Posts: 173
28/10/2018 3:51 pm  
Posted by: maxzax
Thanks for the response oswaldosalcedo,

Do you suffer from any negative symptoms of having low estrogen levels?

Thanks!!
Max

no way, max.
before use anti e`s take a estradiol blood test (for you)

dr frankenstein


ReplyQuote
ersatz
(@ersatz)
Active Member
Joined: 12 months ago
Posts: 9
28/10/2018 4:40 pm  

Does aromasin also bind to the AR and act as an anti-androgen like it's close analog ATD?


ReplyQuote
Big Cat
(@big-cat)
Member Moderator
Joined: 1 year ago
Posts: 313
28/10/2018 5:14 pm  
Posted by: ersatz
Does aromasin also bind to the AR and act as an anti-androgen like it's close analog ATD?

It seems to show a very slight affinity for the AR, but data seems to suggest it has agonist rather than antagonist activity. 0.2% of DHT is the number they came up with, so it would be insignificant either way.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


ReplyQuote
Page 1 / 2
Share:
  
Working

Please Login or Register