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Topic starter
28/10/2018 6:38 am
Hey Guys,
I like to know if you could help me out.
I was looking at getting some aromasin to lower my estrogen levels. My total E's are high (219 range 40-115) and E2 levels are at the top of the reference range. Which I believe is causing HPTA suppression.
From the information I've read Arimidex doesn't make much of a difference in total E's and I've read from other's experiences that aromasin will lower total E's, so I am looking at using aromasin.
I've read that aromasin is a suicide Estrogen Inhibitor, if I lower my Estrogen levels too much with aromasin, will they rebound back to appropriate levels?
Thanks guys!
28/10/2018 7:13 am
Probably higher initially since the absence of estradiol increases presence of both aromatase and the estrogen receptor. THe first weeks following you are likely to have more estrogen and more sensitivity to estrogen.
Good things come to those who weight.
The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.
28/10/2018 8:10 am
BC, to your knowledge is it true that steroidal AI's cause less of a rebound?
28/10/2018 9:07 am
only because they are less potent.
Good things come to those who weight.
The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.
Topic starter
28/10/2018 10:02 am
BC,
If you know of any studies or test results on Aromasin, can you please post them for me.
So based on your information, there would be a large rebound during the first week and after that the levels would stay low?
Btw, thanks for all your knowledge learned a lot from your many posts.
Thanks!
Probably higher initially since the absence of estradiol increases presence of both aromatase and the estrogen receptor. THe first weeks following you are likely to have more estrogen and more sensitivity to estrogen.
28/10/2018 10:46 am
You'd have a large rebound the first few weeks, and then levels of estradiol will normalize again.
Good things come to those who weight.
The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.
28/10/2018 11:39 am
QUOTE]Originally posted by Big Cat
Probably higher initially since the absence of estradiol increases presence of both aromatase and the estrogen receptor. THe first weeks following you are likely to have more estrogen and more sensitivity to estrogen.
not necessarily, i have very low levels of estradiol (under low limits) and i use 2 gr of test (weekly), but my estradiol levels are the same (low always).
to say absence, is extreme,because there is something always.
dr frankenstein
Topic starter
28/10/2018 12:24 pm
Hi oswaldosalcedo,
Was you your low Estradiol caused by using aromasin (exemestane)? If not, what caused the low estradiol levels for you?
What are the side effects your experiencing from having low estradiol levels?
Your answers to the above questions would be much appreciated.
Thank you!!!
Max
28/10/2018 1:01 pm
really i dont know.
genetic predisposition (maybe).
dr frankenstein
Topic starter
28/10/2018 1:32 pm
Thanks for the response oswaldosalcedo,
Do you suffer from any negative symptoms of having low estrogen levels?
Thanks!!
Max
really i dont know.
genetic predisposition (maybe).
28/10/2018 2:20 pm
would tapering armidex avoid the rebound?
what would the taper look like?
Topic starter
28/10/2018 3:05 pm
I believe you want the rebound, because adex and Aromasin are anti E's made for females and could be too strong for men.
Males need estrogen as well for libido, erections and sexual functioning. Too much isn't good and too little isn't good from my understanding.
28/10/2018 3:51 pm
Thanks for the response oswaldosalcedo,Do you suffer from any negative symptoms of having low estrogen levels?
Thanks!!
Max
no way, max.
before use anti e`s take a estradiol blood test (for you)
dr frankenstein
28/10/2018 4:40 pm
Does aromasin also bind to the AR and act as an anti-androgen like it's close analog ATD?
28/10/2018 5:14 pm
Does aromasin also bind to the AR and act as an anti-androgen like it's close analog ATD?
It seems to show a very slight affinity for the AR, but data seems to suggest it has agonist rather than antagonist activity. 0.2% of DHT is the number they came up with, so it would be insignificant either way.
Good things come to those who weight.
The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.
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