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Injecting orals


400mtrackstar
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Can orals like furazabol and halo be injected to avoid the first pass through the liver? Would the process of making it be the same as Test Prop?


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Nytol2
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Dont know specificly about the 2 you mentioned, there is a good chance you could make some kind of injectable with them.

It is much more difficult than making prop etc, 'oral' hormones, do not hold well in oil, so the concentration would need to be greatly reduced, eg with Dbol you can get 25mg in oil.

I am not sure if it would have the desired effect you are after though.


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liftsiron
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I doubt that you would get any noticeable gain from injecting any oral including winstrol. You won't notice any less rise in liver values either.

liftsiron is a fictional character and should be taken as such.


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400mtrackstar
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Posted by: liftsiron
I doubt that you would get any noticeable gain from injecting any oral including winstrol. You won't notice any less rise in liver values either.

Why is that? Wont the first pass through the liver be eliminated? I know Ben Johnson used injectable furazabol but I dont know how he made it or if he injected it to reduce toxicity.


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Big Cat
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First pass through the liver is eliminated, reducing the stress on the liver somewhat, but it still passes the liver eventually, so you won't reduce it that greatly. That's why they call it first pass. There is also a second pass

Like these guys said, no ester, lower lipophillicity, so concentration will likely be no higher than 25 mg/ml and you will have to inject it daily, That means 2 ml daily injections, which may not really be worth it if you ask me.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


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jboldman
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actually first pass usually refers to the cyp p450 metabolism that occurs in the bowel wall along with the liver, avoiding this just increases the eventual load on the liver.

jb


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400mtrackstar
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It will be feasible because its not for a BBer its for a runner which means doses are much lower. I know Ben Johnson would inject 3mg furazabol 3 times a week. Ill try to make a Suspension with 10mg/ml. Thanks guys.


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epote
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quote:


I know Ben Johnson would inject 3mg furazabol 3 times a week. Ill try to make a suspension with 10mg/ml


how do you know that? who told you?

btw, dont go by the cycle CF states at speed trap man, they where designed with very limited (at the time) knowledge for a VERY gifted athlete.

things have changed

"tiss a visitor i muttered
knokcing on my chamber door
only this and nothing more"


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400mtrackstar
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Posted by: epote
how do you know that? who told you?

btw, dont go by the cycle CF states at speed trap man, they where designed with very limited (at the time) knowledge for a VERY gifted athlete.

things have changed

Im not going by that cycle. I also understand how gifted ben johnson is and how gifted I am not to mention we run completely different events. I was just stateing that I know its possible to inject furazabol.


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Nytol2
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I would not try to make it a suspension, try it in oil at 20mg/ml with 4% BA and 15% BB, and see how it goes.

Find out the melting point of furazabol, and heat it to near that temp, I find this is needed with winny to make it hold.

If this does not work, get some guaiacol and post back, and I'll tell you what to do with it.


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400mtrackstar
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Arite thanks nytol2 good looking out.


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400mtrackstar
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Will all hormones filter through a .2u filter?


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DocJ
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Posted by: jboldman
actually first pass usually refers to the cyp p450 metabolism that occurs in the bowel wall along with the liver, avoiding this just increases the eventual load on the liver.

jb

Interesting. That's the first time I've heard that about cyp p450, do you have studies to share?


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jboldman
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really do not need studies, just do a search on "first pass" specifically by p3A4 sub enzyme. most oral drugs are metabolized by the liver , or in the bowel wall as pointed out. if it does not get done one place, it gets done another. one way or another the drug has to get metabolized with the concommitant load on the liver.

jb


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DocJ
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Posted by: jboldman
really do not need studies, just do a search on "first pass" specifically by p3A4 sub enzyme. most oral drugs are metabolized by the liver , or in the bowel wall as pointed out. if it does not get done one place, it gets done another. one way or another the drug has to get metabolized with the concommitant load on the liver.

jb

No matter how it's introduced to the body, it still has to be metabolized down to a certain level. This is actually what I originally thought as well but recently there was a debate on another board that contradicted this line of thinking. I brought it up and everyone started whipping my ass saying I was wrong.


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