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pharmaceutical grade dmso: use to rub on injectables?

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JGUNS
(@jguns)
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Joined: 6 years ago
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The new DMSO bottles come with a pump dispensor, so you could actually pre mix everything and just pump. It is a big pump so you could pretty much get everything through it.


   
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(@ersatz)
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Posted by: pSimonkey
Thanks heavyweight. Anyone know the purpose of sodium hydroxide?

Sodium hydroxide is a strong base which is used ot adjust the ph of the solution. Carbomer 940(a gelling/thickening agent) requires a ph in the range of 5-7, although for transdermal preps I find the range needs to be 7-7.5. If the ph doesn't fall within this range then when you add the carbomer it mixes only with the water soluble compounds.


   
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pSimonkey
(@psimonkey)
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Thank you ersatz, so what is the optimum ph for a transdermal and why?


   
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DocJ
 DocJ
(@docj)
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Posted by: heavyweight
Test 50mg
carbomer 940
ethyl alcohol 68.9%
isopropol myristate
sodium hydroxide
water

forgive me if i'm being dense, what are the % per compound for that formula? thanks...


   
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(@ersatz)
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The optimum ph should be around 7 which makes it fairly neutral. For the carbomer to work, ie thicken the solution into a gel, the ph needs to be in a certain range as previously mentioned.

DocJ: that looks like the ingredients in AndroGel which only had a 10% absorption rate. You can construct better carriers with higher absorption rates closer to 30%.


   
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JGUNS
(@jguns)
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Where are some of you getting your glycerin from?


   
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heavyweight
(@heavyweight)
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Posted by: ersatz

DocJ: that looks like the ingredients in AndroGel which only had a 10% absorption rate. You can construct better carriers with higher absorption rates closer to 30%.

It is androgel, I did say I got it from the doctors. That is why I am using it with DMSO


   
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 SJA
(@sja)
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Just wanted to revive this thread. Has anyone figured out how much carbomer to use per XX ML solution?


   
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