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curcumin and natural testosterone


jboldman
(@jboldman)
Member Moderator
Joined: 6 years ago
Posts: 1448
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for natural athletes, just take care using curcumin.

jb

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Bioorg Med Chem Lett. 2010 Mar 1. [Epub ahead of print]

Curcumin derivatives inhibit testicular 17beta-hydroxysteroid dehydrogenase 3.
Hu GX, Liang G, Chu Y, Li X, Lian QQ, Lin H, He Y, Huang Y, Hardy DO, Ge RS.

School of Pharmacy, Wenzhou Medical College, Wenzhou 325000, PR China.

Non-steroidal compounds that inhibit 17beta-hydroxysteroid dehydrogenase isoform 3 (17beta-HSD3), an enzyme catalyzing the final step in Testosterone biosynthesis in Leydig cells, are under development for male contraceptive or treatment of androgen dependent diseases including prostate cancer. A series of curcumin analogues with more stable chemical structures were compared to curcumin as inhibitors of 17beta-HSD3 in rat intact Leydig cells as well as rat and human testis microsomes. Copyright © 2010 Elsevier Ltd. All rights reserved.


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headdoc
(@headdoc)
Estimable Member
Joined: 6 years ago
Posts: 175
 

this herb is a part of supplement sold as Zyflmend. Works great to reduce inflammation, esp. in joints. Taken on a totally empty stomach can result in some indigestion or burning in the stomach. The manufacturers had listed reduction of chances of PC. The FDA may have stepped in on this one. Just not sufficient data to support the claim.

And we'll collect the moments one by one. I guess that's how the future's done. Feist, "Mushaboom", 2005


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