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Pro-Hormones and Supplements
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Topic starter
16/08/2020 10:17 am
J Int Soc Sports Nutr. 2009 Feb 19;6:6.
The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels.
Spillane M, Schoch R, Cooke M, Harvey T, Greenwood M, Kreider R, Willoughby DS.
Department of Health, Human Performance and Recreation, Baylor University, Box 97313, Waco, TX 76798, USA. [email protected].
Abstract
ABSTRACT: Numerous creatine formulations have been developed primarily to maximize creatine absorption. Creatine ethyl ester is alleged to increase creatine bio-availability. This study examined how a seven-week supplementation regimen combined with resistance training affected body composition, muscle mass, muscle strength and power, serum and muscle creatine levels, and serum creatinine levels in 30 non-resistance-trained males. In a double-blind manner, participants were randomly assigned to a maltodextrose placebo (PLA), creatine monohydrate (CRT), or creatine ethyl ester (CEE) group. The supplements were orally ingested at a dose of 0.30 g/kg fat-free body mass (approximately 20 g/day) for five days followed by ingestion at 0.075 g/kg fat free mass (approximately 5 g/day) for 42 days. Results showed significantly higher serum creatine concentrations in PLA (p = 0.007) and CRT (p = 0.005) compared to CEE. Serum creatinine was greater in CEE compared to the PLA (p = 0.001) and CRT (p = 0.001) and increased at days 6, 27, and 48. Total muscle creatine content was significantly higher in CRT (p = 0.026) and CEE (p = 0.041) compared to PLA, with no differences between CRT and CEE. Significant changes over time were observed for body composition, body water, muscle strength and power variables, but no significant differences were observed between groups. In conclusion, when compared to creatine monohydrate, creatine ethyl ester was not as effective at increasing serum and muscle creatine levels or in improving body composition, muscle mass, strength, and power.
"If we knew what it was we were doing, it would not be called research, would it?"
- Albert Einstein
Topic starter
16/08/2020 11:18 am
Biochem Biophys Res Commun. 2009 Oct 16;388(2):252-5. Epub 2009 Aug 4.
Non-enzymatic cyclization of creatine ethyl ester to creatinine.
Giese MW, Lecher CS.
Department of Chemistry, Marian University, Indianapolis, IN 46222, USA. [email protected]
Abstract
Creatine ethyl ester was incubated at 37 degrees C in both water and phosphate-buffered saline and the diagnostic methylene resonances in the (1)H NMR spectrum were used to identify the resultant products. It was found that mild aqueous conditions result in the cyclization of creatine ethyl ester to provide inactive creatinine as the exclusive product, and this transformation becomes nearly instantaneous as the pH approaches 7.4. This study demonstrates that mild non-enzymatic conditions are sufficient for the cyclization of creatine ethyl ester into creatinine, and together with previous results obtained under enzymatic conditions suggests that there are no physiological conditions that would result in the production of creatine.
It is concluded that creatine ethyl ester is a pronutrient for creatinine rather than creatine under all physiological conditions encountered during transit through the various tissues, thus no ergogenic effect is to be expected from supplementation.
"If we knew what it was we were doing, it would not be called research, would it?"
- Albert Einstein
Topic starter
16/08/2020 11:46 am
Damn it !
I just bought a bunch of CEE.
And throw out my Mono
"If we knew what it was we were doing, it would not be called research, would it?"
- Albert Einstein
Topic starter
16/08/2020 12:07 pm
"If we knew what it was we were doing, it would not be called research, would it?"
- Albert Einstein
16/08/2020 12:25 pm
just take a shit ton of both
16/08/2020 12:44 pm
that's an unfortunate discovery... creatine monohydrate always makes me gain like 10 pounds, not the case with CEE.
16/08/2020 1:04 pm
Nice info.
"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.
16/08/2020 1:31 pm
I've been using both by taking mono on high carb days and cce on lower carb days. The cee is running out tho and I've got plenty of monohydrate
Seabiscuit Hogg is a fictious internet character. It is not recommended that you receive medical advice from fictious internet characters.
SBH :)
Topic starter
16/08/2020 1:50 pm
Howdy Hog !
I hope everything is going good for you .
I've always enjoyed reading your post's .
"If we knew what it was we were doing, it would not be called research, would it?"
- Albert Einstein
16/08/2020 2:06 pm
Hi hotrocks I have to deal with more that my fair share of aholes. Thanks to my friends, I'm making a nice rally tho. Body, soul and spirit!
Seabiscuit Hogg is a fictious internet character. It is not recommended that you receive medical advice from fictious internet characters.
SBH :)
16/08/2020 2:25 pm
The feeling's mutual about posts' hotrocks. I always read all yours. You doing ok?
Seabiscuit Hogg is a fictious internet character. It is not recommended that you receive medical advice from fictious internet characters.
SBH :)
Topic starter
16/08/2020 2:42 pm
Great Brother
Just did a heart stress test and complete blood work so I could go back on a good Test-E cycle and hit the weights hard.
I'm out spray painting some of my plates now, as they have got a little rusty over the years.
Being in my garage doesn't help.
CUL
"If we knew what it was we were doing, it would not be called research, would it?"
- Albert Einstein
16/08/2020 3:05 pm
Test-e is always good. Hope you reach all your goals. Strebgth, size or whatever. Later bro
Seabiscuit Hogg is a fictious internet character. It is not recommended that you receive medical advice from fictious internet characters.
SBH :)