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jboldman
(@jboldman)
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18/08/2020 8:28 am  

interesting to see what the current belief in muscle growth is:

=============Int J Biochem Cell Biol. 2010 Jun 8. [Epub ahead of print]

Human exercise-mediated skeletal muscle hypertrophy is an intrinsic process.
West DW, Burd NA, Staples AW, Phillips SM.

Exercise Metabolism Research Group, Department of Kinesiology, McMaster University.

Abstract
Muscle cells (fibres) are post-mitotic and thus undergo changes in phenotype by modifying their existing structure. Hypertrophy is a hallmark change that occurs in response to increased loading and can be achieved in humans through repeated bouts of resistance exercise (i.e., training). In resistance exercise, contractions are initiated by neural drive leading to immediate perturbations such as calcium influx, cross-bridge cycling and tension/stress on the cytoskeleton, sarcolemma and extracellular matrix, as well as more delayed cellular events such as the production/release of potential local growth factors (e.g., IGF-1). Resistance exercise can also elevate the systemic concentration of certain hormones (growth hormone, testosterone, IGF-1) that are hypothesized to drive hypertrophy. However, while these hormones are clearly anabolic during childhood and puberty, or when given at supraphysiological exogenous doses, the transient post-exercise elevations in hormone concentration are of little consequence to the either the acute protein synthetic response or to a hypertrophic phenotype after resistance training. Thus, the acute post-exercise increases in systemic hormones are in no way a proxy marker for anabolism since they do not underpin the capacity of the muscle to hypertrophy in any measurable way. In contrast, the acute activation of intrinsically located signalling proteins such as p70(S6K) and the acute elevation of muscle protein synthesis are more reflective of the potential to increase in muscle mass with resistance training. Ultimately, local mechanisms are activated by the stress imposed by muscle loading and prime the muscle for protein accretion. Membrane-derived molecules and tension-sensing pathways are two intrinsic mechanisms implicated in upregulating the synthesis and incorporation of muscle proteins into the myofibre in response to mechanical stress derived from loaded contractions. Copyright © 2010. Published by Elsevier Ltd.


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HOTROCKS
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18/08/2020 8:45 am  

quote:


Thus, the acute post-exercise increases in systemic hormones are in no way a proxy marker for anabolism since they do not underpin the capacity of the muscle to hypertrophy in any measurable way.


Unless I don't really understand what they are stating here.
This would go against what I always thought I understood .

HR

"If we knew what it was we were doing, it would not be called research, would it?"
- Albert Einstein


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pillsbury
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18/08/2020 9:11 am  

it seems this is just this guys opinion since there is nothing but his statement that supports this.


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jboldman
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18/08/2020 9:40 am  

correct, it is all the the wording.


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Piston
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18/08/2020 10:07 am  

The end part sounds a lot like a theory touched on by Zatsiorky in Science and Practice of Strength Training. The idea that by catabolizing the proteins through strength training, the muscles became hyper-absorptive ala glycogen stores for endurance athletes.


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Tazmaniac
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18/08/2020 10:34 am  

Did anyone see the full article? I'm wondering what factors they used in their study to fully conclude this or what other variables they may or may not have used.

Disclaimer:
Information that Tazmaniac presents is totally fictitious in nature and is presented for role playing purposes only. The opinions presented do not encourage the use of illegal substances nor take the place of professional medical advice.

Death gotta be easy, cause life is hard...it'll leave you physically, mentally, and emotionally scarred~50 Cent


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jboldman
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18/08/2020 10:57 am  

i could probably get it if anyone is interested


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pillsbury
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18/08/2020 11:20 am  

he did mention acute post-exercise...nothing about what your body is doing after


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Seabiscuit Hogg
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18/08/2020 11:39 am  

Re: Re: Muscle growth

Posted by: Piston
The end part sounds a lot like a theory touched on by Zatsiorky in Science and Practice of Strength Training. The idea that by catabolizing the proteins through strength training, the muscles became hyper-absorptive ala glycogen stores for endurance athletes.

interesting. Is that online anywhere?

Seabiscuit Hogg is a fictious internet character. It is not recommended that you receive medical advice from fictious internet characters.

SBH :)


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Piston
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18/08/2020 12:00 pm  

Zatsiorky's book is one of those of the old Soviet collection. He has continued to update it with a new version out not that long ago. Amazon, etc has it, but I have never seen it as an ebook (doesn't mean it doesn't exist).

He doesn't go into great detail about physiology though -- only brings up the ideas of others as a point of thought.


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Seabiscuit Hogg
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24/08/2020 11:14 am  

I found some stuff online but nothing about carbs/glycogen. This is something I've been playing around with anyway. Kinda goes back to old school "Muscle Media" stuff. When creatine first came out there was a lot of talk about loading carbs and water into muscles to increase leverage and get better lifts. I've used this over the years but never thought it increased actual muscle fiber. All I know is I'm bigger and lifts are going back up. This is a very fascinating area that hasn't been discussed much. I'm going to see if I can track Zatsiorkys' book down.

Seabiscuit Hogg is a fictious internet character. It is not recommended that you receive medical advice from fictious internet characters.

SBH :)


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Seabiscuit Hogg
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24/08/2020 11:33 am  
Posted by: pillsbury
he did mention acute post-exercise...nothing about what your body is doing after

and we all know hormones play a role in that.

Seabiscuit Hogg is a fictious internet character. It is not recommended that you receive medical advice from fictious internet characters.

SBH :)


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Tazmaniac
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24/08/2020 11:55 am  
Posted by: jboldman
i could probably get it if anyone is interested

If it seems like there is interesting in there from the study, then sure...

Disclaimer:
Information that Tazmaniac presents is totally fictitious in nature and is presented for role playing purposes only. The opinions presented do not encourage the use of illegal substances nor take the place of professional medical advice.

Death gotta be easy, cause life is hard...it'll leave you physically, mentally, and emotionally scarred~50 Cent


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