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Estrogen from androstendiol  

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Andy13
(@andy13)
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27/02/2020 2:49 pm  

Something interesting came up in another discussion. Estrogen if primarily formed from the aromatization of testosterone. However, it can also be produced from androstendiol..

Obviously natural T is suppressed during such treament as a fina-only cycle. However, does this necessarily mean androstendiol levels are suppressed as well?


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Big Cat
(@big-cat)
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27/02/2020 3:15 pm  

yes, since the axis is depressed at the pituitary level, no new androgenic precursors are formed from cholesterol, and trenbolone cannot convert into androstenediol.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


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Bilter
(@bilter)
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27/02/2020 3:31 pm  
Posted by: Big Cat
yes, since the axis is depressed at the pituitary level, no new androgenic precursors are formed from cholesterol, and trenbolone cannot convert into androstenediol.

so, based on this one would expects a person running a fina only cycle to have very low levels of estrogen it their system. Correct? If yes, how low would you expect it to go, 50% of normal, 30%??


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Big Cat
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27/02/2020 4:01 pm  

Fina is pretty supressive, and most of the estrogen in the male body is produced through aromatase, so late in a cycle it might even be considerably lower than that. Its the reason why most people stack it with an aromatizing compound for pure muscle gain.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


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jboldman
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27/02/2020 4:30 pm  

i tried to find some references for this but all i ran into were some vague comments in studies that test was the major source of estro via aromatization.

Damn it is nice to have you back on board again bc!

jb


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jboldman
(@jboldman)
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27/02/2020 4:49 pm  

i also wonder if instead of adding in test, if you had it, 300iu of HCG might be a reasonable alternative.

jb


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Big Cat
(@big-cat)
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27/02/2020 5:18 pm  

Well it has been shown that unlike natural LH, high dose HCG has a higher propensity (up to 3 times) to increase estrogen over androgens. That was in fact one of the reasons we started stressing using SERMS all the way through PCT.

I find it a tad harder to control though, because a bolus dose of HCG cause quite the hormone fluctuation.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


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guijr
(@guijr)
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27/02/2020 5:38 pm  
Posted by: jboldman
i tried to find some references for this but all i ran into were some vague comments in studies that test was the major source of estro via aromatization.

Damn it is nice to have you back on board again bc!

jb

Regarding BC, I double that JB.

"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.


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Big Cat
(@big-cat)
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27/02/2020 6:05 pm  

You guys are gonna make me blush, but leafing through my old research this week, I really have to say its good to be back. You can't imagine how I missed this, and now it seems so stupid that I needed a break. But i guess sometimes life requires a little more of your attention.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


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