IGF-1 LR3 protocol info
Have any of you bros used IGF? I would like to know of doses and timing for training and racing.
I have heard that 40 mcg eod is the norm. Anybody have info on injection into specific bodyparts (legs).
You guys are a fountain of info and would like to hear your thoughts.
We have the following information in our files, apologies to the author(s), whose name(s) we do not have on record to give proper credit.
The most effective length for a cycle of IGF is 50 days on and 20-40 days off. The most controversy surrounding Long R3 IGF-1 is the effective dosage. The most used dosages range between 20mcg/day to 120+mcg/day. IGF is only available by the milligram, one mg will give you a 50 day cycle at 20mcg/day, 2mg will give you a 50 day cycle at 40mcg/day, 3mg will give you a 50 day cycle at 60mcg/day, 4mg will give you a 50 day cycle at 80mcg/day and so on. IGF is most effective when administered subcutaneously and injected once or twice daily at your current dosage. The best time for injections is either in the morning and/or immediately after weight training.
Weeks 1-5, 11-15, (21-25) � Long R3 IGF-1 � Every day
60-80 mcg�s intramuscular
� post work out on workout days
� first thing in the morning on non workout days
(alternately 1/2 am, 1/2 post workout if desired ... recommended if dosage is 80mcgs or above)
When HGH makes it pass through the liver, a release of IGF-1 is a result. IGF-1 appears to be the key player in muscle growth. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. While HGH will cause an increase in your IGF-1 level over the course of a few months, HGH has a cumulative effect, so the addition of IGF-1 will greatly speed up the time to results.
There are two types of IGF-1 that will typically be used by bodybuilders. One is bio-identical huIGF-1, a 70 amino acid string. The other is Long R3 IGF-1, which is an 83 amino acid analog of human IGF-I comprising the complete human IGF-I sequence with the addition of a "side chain" - a substitution of an Arg for the Glu at position 3 (hence R3), and a 13 amino acid extension peptide at the N-terminus (hence the long). This 13 amino acid "side chain" helps prevent the IGF-1 from being so easily bound by IGF binding proteins, and thus increases its active window exponentially. Which of these you use depends on your goal.
HuIGF-1 is very short lived in the body (half life of probably around 10 minutes). This type of IGF-1 is very useful if you are seeking local site growth. Since it is so short lived, little of the IGF-1 makes it to other tissues and IGF-1 receptors in the body. The way to inject this is immediately post work out into the muscle that you wish to have local site growth. Use a U100 insulin syringe, and inject ~120-200mcg�s bilaterally into the desired muscle immediately post workout. For this type of IGF-1, I would use it workout days only or if desired you could inject on non-workout days first thing in the morning into a muscle group worked the previous day.
For Long R3 IGF-1, it isn�t critical that you inject into a local site as long R3 has a active window of many hours, and is designed specifically to resist being bound by IGF binding proteins, so it will certainly make its way through the body before its active life is through.
Since it is common to reconstitute this type of IGF-1 with Acetic Acid, Hydrochloric Acid, or Benzyl Alcohol, I would recommend that you inject intra-muscular. While for some purposes of nerve regrowth, etc. subQ is a somewhat superior injection method, it can and probably will leave a nice red irritated spot for a good amount of time if you inject subQ, and it is not superior for muscle growth purposes anyway.
I still inject into a muscle just worked to take advantage of increased IGF-1 receptors present as a result of tearing down muscles with workout, but because of the long activity window of this type of IGF-1 any muscle will work well and give you good results,. I would suggest that you inject between 60-120 mcg�s per day everyday immediately post workout on workout days, and first thing in the morning on non-workout days, or alternately 1/2 in the am and 1/2 post workout.
Use a U-100 insulin syringe with 1/2" needle to inject IGF-1 intramuscular (bilaterally for HuIGF-1, bilaterally not necessary for Long R3)
you might want to ask opinions, mine is quite widely known, in the few times i have tried it, as recently as 6 months ago at 60mcg/day it was basically useless. i would much rather spend the money on hgh or i suppose epo. definitely test would be a better buy.
in fairness, some swear by it, but, alas, it has never seemed to work for me.
i do not want to mention names here since the results are variable. You are correct in that the prices are coming down. I think a real issue is that this stuff all comes from one lab that i know of, has never been sanctioned for huiman use, must be treated very gently during shipping and mixing. THere are just a lot of variables that can make the stuff worthless.
However for $100 it might be worth a try. your mileage will definitely vary. If money is short, i would suggest something else with a more stable track record.