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guijr
(@guijr)
Honorable Member
Joined: 1 year ago
Posts: 732
09/07/2019 6:36 pm  
Posted by: HitMeBack
I would hardly say 250-300mg of test/week is a barely effective dose!

Maybe just for the crazy responders like me .

"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.


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ready2explode
(@ready2explode)
Reputable Member
Joined: 1 year ago
Posts: 301
09/07/2019 7:07 pm  

According to the study I posted (which reminds me I have to find the one on the safety of such a cycle), 300mgs a week over 20 weeks yields a 5.2kg gain in fat-free mass (11.44lbs). That's not a shabby amount of weight, but when taken in the context of the length of the cycle...that changes things a bit.

"In any contest between power and patience, bet on patience."
~W.B. Prescott

"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein


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Zircon
(@zircon)
Estimable Member
Joined: 1 year ago
Posts: 165
09/07/2019 7:32 pm  

Originally posted by Zircon
holy fook!! lol 60mg Dbol and 100mg winny?

And I stress abotu taking prop at 150mg for 2 weeks hahahaaaaaaaaaa
--------------------------------------------------------------------------------

Pretty retarded imo!!!!

>> what the 2 weeks of prop I do or the 100mg winny and 60,g dbol\?? lol


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oswaldosalcedo
(@oswaldosalcedo)
Estimable Member
Joined: 1 year ago
Posts: 217
09/07/2019 7:58 pm  
Posted by: guijr
Maybe you may cut the cortisol but I don't think that it would do anything for HPTA downregulation.

CRH, ACTH and TSH values keep normal.
with the use of enantathe,cypionate,decanoate etc, they go awry, dysregulation takes place, be downregulation or upregulation it depends which hormone or organ is implicated,hypothalamus or pituitary.

i take orals only on workout days (3-4 on,3 off) taking them at 6:00 am.After 4:00 pm there is less activity of dbol or winny (active life 6-8 hours),and the 3 days off,this way, there is receptor binding limited action, long acting roids (extended release,ester attached) can have more constant time on GR receptors or AR receptors in antagonistic or agonistic action on hypothalamus or pituitary.

J Neuroendocrinol. 2001 May;13(5):442-52.

Androgens alter corticotropin releasing hormone and arginine vasopressin mRNA within forebrain sites known to regulate activity in the hypothalamic-pituitary-adrenal axis.

Viau V, Soriano L, Dallman MF.

J Neuroendocrinol. 2004 Mar;16(3):272-8.

Androgen inhibits, while oestrogen enhances, restraint-induced activation of neuropeptide neurones in the paraventricular nucleus of the hypothalamus.

Lund TD, Munson DJ, Haldy ME, Handa RJ.

Neuropsychopharmacology. 2003 Jun;28(6):1056-67.

Effect of chronic administration of selective glucocorticoid receptor antagonists on the rat hypothalamic-pituitary-adrenocortical axis.

Bachmann CG, Linthorst AC, Holsboer F, Reul JM.

Neuroscience. 2005;130(2):427-34.

A single dose of metyrapone caused long-term dysregulation of the hypothalamic-pituitary-adrenal axis in the rat.

Rotllant D, Armario A.

dr frankenstein


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Black Baccara
(@black-baccara)
Trusted Member
Joined: 1 year ago
Posts: 87
09/07/2019 8:16 pm  
Posted by: oswaldosalcedo
active life 6-8 hours

What do you mean by "active life" ?


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oswaldosalcedo
(@oswaldosalcedo)
Estimable Member
Joined: 1 year ago
Posts: 217
09/07/2019 8:33 pm  
Posted by: Black Baccara
What do you mean by "active life" ?

active half life.
The half-life may be defined as the time (t) the level is half of the starting level of a given compound; at time 2t, the level is a quarter of the starting level, and at time 3t, the level is an eighth of the starting level, and so on.

Oral steroids

Drug Active half-life

Dianabol- methandrostenolone 4.5 to 6 hours
Anavar - oxandrolone 9 hours
Methyltestosterone 4 days
Anadrol - oxymetholone 8 to 9 hours
winstrol -Stanozolol 9 hours.

next time, I don't use winny.

dr frankenstein


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Black Baccara
(@black-baccara)
Trusted Member
Joined: 1 year ago
Posts: 87
09/07/2019 8:56 pm  
Posted by: oswaldosalcedo
active half life.
The half-life may be defined as the time (t) the level is half of the starting level of a given compound; at time 2t, the level is a quarter of the starting level, and at time 3t, the level is an eighth of the starting level, and so on.

I know what is half-life ( ), I ask for "active life".


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oswaldosalcedo
(@oswaldosalcedo)
Estimable Member
Joined: 1 year ago
Posts: 217
10/07/2019 7:00 am  
Posted by: Black Baccara
I know what is half-life ( ), I ask for "active life".

correct,teacher ......lol.........
so predictable.
wooowwwwww so bright!

active life can be 2.5-3 times.

dr frankenstein


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jboldman
(@jboldman)
Member Moderator
Joined: 1 year ago
Posts: 1023
10/07/2019 7:18 am  

so what is "active half-life?" is it different form palin old half-life. and while we are at it differentiate between that and elimination half-life.

jb


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