Oxymetholone  

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gtrack
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03/12/2018 2:11 pm  

Nolva ,ralox and toremifen block estrogen action on site,meaning estrogen can be present in the bloodstream but be preventing from acting on the breast gland and tissue.Depending on the substance it could let estrogen action uninhibited or not in bone,uterus etc.
Arimidex,aromasin and femara and some others block the conversion of androgens to estrogens and decrease the estrogen levels in the blood that occur this way.
If Anadrol acts as an estrogen,only nolva and the rest of that family can help.
If it converts to estrogen then an aromatase inhibitor can help reduce this conversion and nolva can help nullify any effect on the breast.

From what i gather it seems oxymetholone doesn't convert to estrogen (maybe because it's dht derived ? ) but acts like one,so nlva might be the only solution.But i'd wait for confirmation from BC or BB before i proceed to do anything.
So far i know it doesn't act like a progestin which is great.


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ready2explode
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03/12/2018 4:18 pm  
Posted by: Interficium
I've noticed that after using anadrol the HTPA recovery is much longer. If it isn't the progestin acting, what migth be?

Have you gotten your blood work done? Keep in mind, you can't go on "feel" to judge if you've recovered or not. It needs to be tested.

"In any contest between power and patience, bet on patience."
~W.B. Prescott

"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein


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ready2explode
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03/12/2018 5:14 pm  
Posted by: guijr
What is the daily dosage to prevent gyno?

This will vary. Most get away with 30mgs of tamox citrate, but you may need more.

"In any contest between power and patience, bet on patience."
~W.B. Prescott

"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein


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ready2explode
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03/12/2018 6:07 pm  
Posted by: guijr
BC, how many mg of nolva do you consider a high dose?

And what is your opinion about anadrol regarding muscle and strength gains?

Are its side effects really a concern?

Minimum and maximum dose in order to promote gains and avoid sides?

Below you'll see a graph where relative (%) changes in strength are shown for the groups receiving placebo (filled bars), 50 mg/day oxymetholone (open bars), and 100 mg/day oxymetholone (gray bars). Nos. above bars represent relative change (%) from baseline to week 12 for the 1-repetition maximum tests of strength. Error bars represent � 1 SE from the mean. * Significant difference from placebo, P < 0.05; significant difference from placebo by Wilcoxon test, P < 0.02. See text for additional statistical analyses.

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"In any contest between power and patience, bet on patience."
~W.B. Prescott

"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein


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ready2explode
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03/12/2018 6:50 pm  
Posted by: guijr
BC, how many mg of nolva do you consider a high dose?

And what is your opinion about anadrol regarding muscle and strength gains?

Are its side effects really a concern?

Minimum and maximum dose in order to promote gains and avoid sides?

In this graph, changes in body composition are shown for the groups receiving placebo (filled bars), 50 mg of oxymetholone per day (open bars), and 100 mg per day (gray bars). Numbers above the bars represent the mean absolute changes and the error bars are � 1 SE. For total lean body mass (LBM) and total fat, differences among the 3 groups were significant (P < 0.0001, one-way ANOVA). * Significant differences from placebo, P 0.001.

This post was modified 1 year ago by Admin

"In any contest between power and patience, bet on patience."
~W.B. Prescott

"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein


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ready2explode
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03/12/2018 7:22 pm  
Posted by: guijr
BC, how many mg of nolva do you consider a high dose?

And what is your opinion about anadrol regarding muscle and strength gains?

Are its side effects really a concern?

Minimum and maximum dose in order to promote gains and avoid sides?

More:

Oxymetholone for the treatment of HIV-wasting: a double-blind, randomized, placebo-controlled phase III trial in eugonadal men and women.

Hengge UR, Stocks K, Faulkner S, Wiehler H, Lorenz C, Jentzen W, Hengge D, Ringham G.

Department of Dermatology, University of Dusseldorf, Dusseldorf, Germany.

BACKGROUND: Despite highly active antiretroviral therapy (HAART), chronic involuntary weight loss still remains a serious problem in the care of HIV patients due to various alterations in energy metabolism and endocrine regulation. Previous studies in HIV-positive men undergoing androgen replacement therapy or treatment with recombinant growth hormone (rGH) have shown partial restoration of lean body mass (LBM), but these treatments have largely not been sufficiently studied in eugonadal individuals. METHOD: A double-blind, randomized, placebo-controlled trial of 89 HIV-positive eugonadal women and men with wasting assigned to the anabolic steroid oxymetholone (50 mg bid or tid) or placebo for 16 weeks was performed. Body weight, bioimpedance measurements, quality of life parameters, and appetite were analyzed. RESULTS: Oxymetholone led to a significant weight gain of 3.0 +/- 0.5 and 3.5 +/- 0.7 kg in the tid and bid groups, respectively (p <.05 for each treatment versus placebo), while individuals in the placebo group gained an average of 1.0 +/- 0.7 kg. Body cell mass (BCM) increased in the oxymetholone bid group (3.8 +/- 0.4 kg; p <.0001) and in the oxymetholone tid group (2.1 +/- 0.6 kg; p <.005). Significant improvements were noted in appetite and food intake, increased wellbeing, and reduced weakness by self-examination. The most important adverse event was liver-associated toxicity. Overall, 43% of patients in the tid group, 25% of patients in the bid oxymetholone group, and 8% in the placebo group had a greater than 5 times baseline increase for ALT, AST, or gamma GT, while other adverse events were not increased over placebo.CONCLUSION: Oxymetholone can be considered an effective anabolic steroid in eugonadal male and female patients with AIDS-associated wasting. The bid (100 mg/day) regimen appeared to be equally effective to the tid (150 mg/day) regimen in terms of weight gain, LBM, and BCM and was associated with less liver toxicity.

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"In any contest between power and patience, bet on patience."
~W.B. Prescott

"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein


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HugeDeep
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03/12/2018 8:02 pm  

Oxymetholone seems to work well with others like winny and Primobolan......just not TEST. Here is a good read on it.

Oxymetholone

"SPES ET FIDES"


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guijr
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03/12/2018 8:45 pm  

Informative post r2e, but what's your opinion about Anadrol?

And if one is planning to use it, what would be some basic steps (eg. maximum number of weeks, dose, protections [liver, blood pressure etc.]) to follow?

"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.


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ready2explode
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03/12/2018 9:28 pm  
Posted by: HugeDeep
Oxymetholone seems to work well with others like winny and Primobolan......just not TEST. Here is a good read on it.

That profile is horribly outdated, and full of flaws.

This post was modified 1 year ago by Admin

"In any contest between power and patience, bet on patience."
~W.B. Prescott

"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein


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ready2explode
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04/12/2018 6:35 am  
Posted by: HugeDeep
Oxymetholone seems to work well with others like winny and Primobolan......just not TEST. Here is a good read on it.

That profile is horribly outdated, and full of flaws.

This post was modified 1 year ago by Admin

"In any contest between power and patience, bet on patience."
~W.B. Prescott

"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein


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ready2explode
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04/12/2018 7:20 am  
Posted by: guijr
Informative post r2e, but what's your opinion about Anadrol?

And if one is planning to use it, what would be some basic steps (eg. maximum number of weeks, dose, protections [liver, blood pressure etc.]) to follow?

My position on anadrol is similar to my position with other orals, limit their use. Side effects are worse from them than with injectables, but not enough of a difference to warrant their use.

I'd recommend keeping intake to 6 weeks max, four weeks is my personal limit. According to the study, 150mgs isn't much better than 100mgs, and therefore would recommend the lower of the two.

As for your liver, I don't believe their is anything you can take during your cycle that will help, not even a bit. After the cycle, liver protectants, such as milk thistle, can be used to help your liver recover.

"In any contest between power and patience, bet on patience."
~W.B. Prescott

"Only two things are infinite, the universe and human stupidity, and I'm not sure about the former."
~Albert Einstein


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Big Cat
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04/12/2018 7:57 am  
Posted by: gtrack
Wait,converts to estrogen or acts like one ? If it's about conversion then aromasin should be the better choice here.

Acts like one, or at least one of its metabolites does. regardless, aromatase is not involved, so an AI would be useless. But then, that is how I generally feel about AI's anyway.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


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Big Cat
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04/12/2018 8:55 am  
Posted by: HugeDeep
Oxymetholone seems to work well with others like winny and Primobolan......just not TEST. Here is a good read on it.

 

Good lord, there are really still people (let alone on this board) who think there is such a thing as classI and classII steroids ?

This post was modified 1 year ago by Admin

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


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Big Cat
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04/12/2018 9:42 am  
Posted by: guijr
BC, how many mg of nolva do you consider a high dose?


40 and up.

quote:


And what is your opinion about anadrol regarding muscle and strength gains?


Decent, especially for an oral. Rather hard to keep, and I feel you can't get the maximum out of it, because a lot of people feel like crap while taking it. But its certainly an effective drug.

quote:


Are its side effects really a concern?


Yes. Though liver issues are often exaggerated. Liver values tend to rise faster, but in the end seem to get no higher than from common (in my book) doses of other drugs : 80 mg oxa, 100 mg stana, 40mg Dbol. And less than what you'd see for halo, M1T or Superdrol, even in doses of 150-200 mg a day. Though there are conflicting studies on it, I remember one, its posted on medibolics, where people took 200 mg a day for 20 weeks with no major adverse effects.

A bigger concern in my book is the effect it has on your blood pressure. Bloat, headaches, lethargy are all fairly common with use of anadrol, making it not the most user friendly drug.

quote:


Minimum and maximum dose in order to promote gains and avoid sides?

I'd keep it around 100 mg a day for the best benefit to side ratio.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


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Seabiscuit Hogg
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04/12/2018 10:13 am  
Posted by: Big Cat
Good lord, there are really still people (let alone on this board) who think there is such a thing as classI and classII steroids ?

Isn't the idea of winny being an anti-progestagenic kinda dated too? If oxmetholone causes estrogenic sides by acting directly on the ER, winny wouldn't help. Personally, I don't get bloating or other sides from anadrol but I know a lot of ppl who do.

Seabiscuit Hogg is a fictious internet character. It is not recommended that you receive medical advice from fictious internet characters.

SBH :)


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