Is HGH the pinnacle of Anabolism?
Is it the best BB supp?
Does it have sides when you stop use (ie. gain loss, libido damage, lethargy, etc?)
Who has experienced big growth on Growth?
struggle---and shine on
Just because there is a goalie, doesnt mean you can't score.
Satisfaction is the death of desire.
Practice makes perfect; and I love 2 practice!!
I've never done GH, but I thought exo GH and L3-IGF were supposed to induce hyperplasia if not hypertrophy........ is this no longer the case?
"You still got the tools, but they're different" (Angelo Dundee => Muhammad Ali)
leaning out a bit
"One guy thinks he can, another guy thinks he can't. Both are right. Which one are you son?" (Nike commercial football coach)
well for the money i mean it is a waste when used alone. i have used aas alone and also with gh and insulin and i can tell you from my experience i had significantly better gains with AAS plus gh/insulin. i have also used aas and gh alone and also had better gains than i did with just aas alone. now i have experimented and have done gh alone when off cycle and noticed next to nothing except maybe i stayed leaner. i know nandi is not a big fan of gh when used alone. i am not sure whether he thinks gh when used with aas and insulin is synergistic.
Clin Endocrinol (Oxf). 2005 Apr;62(4):449-57. Related Articles, Links
Supraphysiological growth hormone: less fat, more extracellular fluid but uncertain effects on muscles in healthy, active young adults.
Ehrnborg C, Ellegard L, Bosaeus I, Bengtsson BA, Rosen T.
Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Sahlgrenska University Hospital, Goteborg, Sweden.
Summary Objectives To study the effects on body composition after 1 month's administration of supraphysiological doses of growth hormone (GH) in healthy, active young adults with normal GH-IGF-I axis. Subjects and methods Thirty healthy, physically active volunteers (15 men and 15 women), mean age 25.9 years (range 18-35), participated in this study, designed as a randomized, double-blind, placebo-controlled, parallel study with three groups (n = 10: five men and five women in each group). The groups comprised the following: placebo (P), GH 0.1 IU/kg/day [0.033 mg/kg/day] (GH 0.1) and GH 0.2 IU/kg/day [0.067 mg/kg/day] (GH 0.2). Results In the pooled group with active GH treatment (n = 20) the results showed significant increases: IGF-I increased by 134% (baseline vs. after 1 month), body weight by 2.7%, fat free mass by 5.3%, total body water by 6.5% and extracellular water (ECW) by 9.6%. Body fat decreased significantly by 6.6%. No significant change in intracellular water was detected. The observed increase in fat free mass by 5.3% was explained by the ECW increase, indicating limited anabolic effects of the supraphysiological GH doses. Changes were noticeable in both genders, although more prominent in the male subjects. Fluid retention symptoms occurred in the majority of individuals. Conclusions This is, to our knowledge, the first placebo-controlled trial to show the effects of supraphysiological GH doses on body composition and IGF-I levels in physically active and healthy individuals of both genders; the results indicate limited anabolic effects of GH with these supraphysiological doses. The role of GH as an effective anabolic doping agent is questioned.
PMID: 15807876 [PubMed - in process]
Why are all the hgh studies only short term. It is common knowledge that it takes at least 3-4 months for benefits through hyperplasia to take place, I really doubt scientists are this ignorant. Maybe they are trying to lessen its exploitation in the bb world through publishing studies like these.
god ! people criticize, but, but they do not investigate!
and for kml0331
again a great article!
Whole body and regional soft tissue changes in growth hormone deficient adults after one year of growth hormone treatment: a double-blind, randomized, placebo-controlled study.
Hansen TB, Vahl N, Jorgensen JO, Christiansen JS, Hagen C.
Department of Internal Medicine and Endocrinology, Odense University Hospital, Denmark.
OBJECTIVE: Adults with GH deficiency (GHD) exhibit changes in body composition. Studies of the effects of GH substitution on body composition have been short-term or not adequately controlled. The purpose of this study was to evaluate the long-term effects of GH on soft tissue using dual-energy X-ray absorptiometry (DEXA). This technique enables assessment of whole body as well as regional soft tissue composition. DESIGN: A double-blind, randomized, placebo-controlled study in patients with acquired GHD. The therapeutic regime consisted of biosynthetic human GH ( 2.0 IU/m2 per day) or placebo, given as a daily subcutaneous injection at 2000 h for 12 months. PATIENTS: Twenty-nine patients with acquired GHD (GH < 10 micrograms/l (< 20 mU/l) following standard provocative tests) in whom additional hormone replacement was maintained. MEASUREMENTS: Soft tissue determinations by DEXA scan, height, weight, foot volume and finger circumference were recorded together with serum IGF-I at baseline and after 12 months. RESULTS: Twelve months of GH therapy induced a total fat mass (FM) reduction of (mean +/- SEM) 4.88 +/- 0.58 kg (P < 0.002) (n = 13) corresponding to 21.5% of the total FM. The reduction in fat was most marked in the trunk, i.e. 3.07 +/- 0.29 kg (P < 0.002) corresponding to 61% of the total FM reduction. Total lean soft tissue mass (LSTM) increased by 3.31 +/- 0.81 kg (P < 0.001). Regional changes for arm and leg in the GH group amounted to 0.32 +/- 0.08 kg (P < 0.002) and 0.71 +/- 0.14 kg (P < 0.002), respectively, without accompanying significant changes in truncal LSTM between the groups. The foot volume was increased by 55.8 +/- 15.7 ml (P < 0.007) and the finger circumference by 2.67 +/- 0.5 mm (P < 0.005) on active treatment with no significant changes in the placebo group. CONCLUSIONS: Twelve months of GH therapy induced marked changes in soft tissue; fat mass was reduced, particularly in the trunk (61% of total fat mass reduction) whereas lean soft tissue mass increased more in the extremities. The data imply that GH-induced changes in body composition are maintained with long-term therapy.
5 kg a year for 4 ius daily