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Could It Be That Deca Is The Liver Silver Bullet?


jboldman
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we all know that 17aa orals are poison to our livers and that injectables, in general, are far easier on our livers. could it be that nandrolone is the key to restoring our livers to good health?

jb

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Anabolic steroid nandrolone augments hepatic regenerative response in rats.Sileri P, Palmieri G, Gentileschi P, Perfetti A, Sica G, Venza M, Benavoli D, Gaspari AL.
Department of Surgery, University of Rome Tor Vergata, Rome, Italy.

The success of recovery after liver resection depends on the regeneration and functions of the remnant liver. In this study we investigated whether liver regeneration was facilitated by nandrolone decaonate after two-thirds partial hepatectomy in rats. Study animals were pretreated with nandrolone (5 mg/kg), while control animals received a placebo. Animal were sacrificed at 12, 24, 48, and 72 hours. We compared the survival rates, liver function tests as well as the amount of apoptosis by terminal deoxynucleotidyl transferase-mediated deoxyuridine-biotin nick end labeling assay, and regeneration, which was expressed as ratio of proliferating cell nuclear antigen and restoration ratio. A significant increase in hepatocyte regeneration at 24 and 48 hours in partially hepatectomized rats treated with nandrolone decaonate was observed compared to controls. This observation was confirmed by the significant acceleration of the liver restoration rate, which was 1/5 faster than in partially hepatectomized controls. The results of this study indicate that liver regeneration in rats treated with nandrolone show a prompt, faster regeneration after partial hepatectomy.

This topic was modified 3 years ago by jboldman

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liftsiron
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Nice!

liftsiron is a fictional character and should be taken as such.


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needsize
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That is very interesting.


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DocJ
 DocJ
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Do you think this is specifically nandrolone that does this? Wouldn't test do the same? These researchers need to start using test instead of nandrolone in their studies...or better yet, use both and compare.


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guijr
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Very important post. Just a speculation, but maybe if a guy wants to include an oral drug like Anadrol in his cycle, so deca would do the trick.

"The medals don't mean anything and the glory doesn't last. It's all about your happiness. The rewards are going to come, but my happiness is just loving the sport and having fun performing" ~ Jackie Joyner Kersee.


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jboldman
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i could speculate that the researchers had reason to suspect nandrolone might work rather than test but i agree, it would have been nice to do a parallel test.

Yes, this very well might be a good reason to include nandrolone with orals in a cycle. now maybe that old saying "if you cant grow on Dbol and deca you cant grow on anything" makes a little more sense.

jb
(who does NOT recommend orals)


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saint808
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Next time my liver panel is off I am totally taking a printed copy of that in with me to the doctor.

Disclaimer:
saint808 is presenting fictitious opinions and does in no way, shape or form encourage, use nor condone the use of any illegal substances or the use of legal substances in an illegal manner. The information discussed is strictly for entertainment purposes only and shall not take the place of qualified medical advice.

To quote Oscar Wilde, "They say we destroy the things we love, but really the things we love destroy us."

It's strange, how laughter looks like crying, with no sound and rain drops taste like tears, without the pain.


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Big Cat
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Do you have the full study ?

My guess its merely the anabolic component that increased tissue regeneration after trauma in general (hepatectomy). I don't think this implies that steroids, or deca in particular, will counteract liver damage as a result of liver-stressing drugs such as alcohol and 17AA.

Good things come to those who weight.

The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.


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DocJ
 DocJ
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Posted by: Big Cat
My guess its merely the anabolic component that increased tissue regeneration after trauma in general (hepatectomy).

This is what I thought as well...


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jboldman
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Testosterone treatment of men with idiopathic hemochromatosis.Kley HK, Stremmel W, Kley JB, Schlaghecke R.
Stadtisches Krankenhaus, Singen/Hohentwiel, Heinrich-Heine-Universitat, Dusseldorf.

Patients with chronic liver disease usually exhibit low plasma levels of testosterone with loss of libido and potency; this is also valid in male patients suffering from idiopathic hemochromatosis (IHC), in whom nowadays the diagnosis is made at an earlier age. Therefore, the effect of testosterone treatment was studied in 10 patients with IHC. After the application of 250 mg Testosterone Enanthate i.m., the plasma testosterone (from 2.4 +/- 1.9 to 20.1 +/- 7.4 ng/ml) and estradiol (from 17.4 +/- 6.3 to 38.5 +/- 14.2 pg/ml) levels increased significantly. The rise of estradiol was in the range of controls and smaller than reported in other chronic liver diseases. In a long-term study, 250 mg testosterone enanthate was given 4-weekly for 33-96 months to 5 patients with IHC. General well-being, libido, and potency recovered almost immediately. Over a treatment period of 27.3 patient years, symptoms of hyperestrogenism (gynecomastia) or (portal vein) thrombosis were not seen, both of which had been described in patients with alcoholic liver cirrhosis. There was no deterioration of liver function. The effect of testosterone treatment on the patients' well-being and plasma hormone concentrations remained unchanged over the whole period of testosterone treatment. Thus, in male patients with IHC and lowered plasma testosterone, treatment with testosterone enanthate may be instituted. Because of the positive effects on general well-being, liver regeneration capacity, and potency, testosterone should especially be administered to younger subjects suffering from IHC.


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