Notifications
Clear all
15/05/2019 1:45 pm
Re: Re: Re: Re: Re: Non-aromatase related estrogenic effects from androgen use
You have some real drama issues ...I question the outcome of that if you get the same results on estradiol levels using femara or Nolvadex, since femara should drastically reduce estrogen, whereas nolvadex should slightly elevate estradiol (since it doesn't change production of estrogen, but it does displace it from the receptor resulting in more serum-borne estradiol). which in turn questions the validity of any other results you present as being from blood tests.
There are many ways to reduce 5-alpha-reduction. However, I fail to see why you mention it, if it is your contention that aromatase blocking does not raise systemic DHT ?
quote:
men taking 5AR blockers experience higher estrogen, and estrogenic problems, same holds true for aromatase blockers....
not my case,ever around 8 pg/ml.
-------------------------------------------------
quote:
since femara should drastically reduce estrogen....
cannot go down any more!
dr frankenstein
15/05/2019 2:22 pm
BigCat,
I haven't been able to fully understand what you have told me. Perhaps we are misunderstanding each other.
I still cannot understand why your DHT levels would raise when you block aromatase. You say that there should be no change in enzyme levels and, at the same time, you agree with me in that estrogen "freed" from Testosterone is tiny (0.1-1%?), so why would DHT go up?
P.D.: do you have any reference which demonstrates DHT is an aromatase inhibitor?
thanks.
Topic starter 15/05/2019 3:48 pm
ER-mediated effects by stanozolol
Nice find
And we also know stanozolol to be a mild progestin, and if it follows suit with danazol, probably a mild glucocorticoid, and definitely a modulator of glucocorticoid activity. If it has mineralocorticoid activity it would probably be the most ambiguous agonist of classic nuclear receptors
Good things come to those who weight.
The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.
15/05/2019 4:22 pm
Re: Re: Re: Re: Re: Re: Non-aromatase related estrogenic effects from androgen use
BigCat,I haven't been able to fully understand what you have told me. Perhaps we are misunderstanding each other.
I still cannot understand why your DHT levels would raise when you block aromatase. You say that there should be no change in enzyme levels and, at the same time, you agree with me in that estrogen "freed" from testosterone is tiny (0.1-1%?), so why would DHT go up?P.D.: do you have any reference which demonstrates DHT is an aromatase inhibitor?
thanks.
correct,because:
5alpha reduction is quantitatively in the same order as aromatisation, and blocking either enzyme has shown to elevate output of the other. men taking 5AR blockers experience higher estrogen, and estrogenic problems, same holds true for aromatase blockers.
???
dr frankenstein
Topic starter 15/05/2019 4:54 pm
Do you ever form full sentences ?
Good things come to those who weight.
The Big Cat is a researcher and theoreticist. His advice must never be taken in the stead of proper advice from a medical professional, it is entirely intended for research purposes.
15/05/2019 5:38 pm
Bump!
Hall of fame
How about a summary of this advanced discussion? I think that would please most of us
Page 4 / 4 Prev